Customization: | Available |
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CAS No.: | 520-27-4 |
Formula: | C28h32o15 |
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Items | Requirements | Result |
Appearance | Greyish-yellow or light yellow, hygroscopic powder | Complies |
Solubility | Practically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in ethanol (96%), it dissolves in dilute solution of alkali hydroxides. | Complies |
Identification | A) IR: Complies diosmin CRS B) HPLC: Complies to the reference solution |
Complies |
Iodine | ≤0.1% | Complies |
Water | ≤6.0% | 3.97% |
Sulphated Ash | ≤0.2% | 0.07% |
Heavy Metals | ≤20ppm | Complies |
Particle Size | NLT95% pass 80 mesh | Complies |
Related Substances | Impurity A(Acetoisovanillone)≤0.5% | 0.03% |
Impurity B(Hesperidin)≤4.0% | 0.86% | |
Impurity C(Isorhoifolin)≤3.0% | 2.60% | |
Impurity D(6-iododiosmin)≤0.6% | 0.42% | |
Impurity E(Linarin)≤3.0% | 2.16% | |
Impurity F(Diosmetin)≤2.0% | 0.36% | |
Unspecified Impurities(each)≤0.4% | 0.35% | |
Total Impurities≤8.5% | 6.78% | |
Assay (Anhydrous substance, HPLC) | 90.0%~102.0% | 91.37% |
Residual Solvents | Pyridine≤200ppm | 121ppm |
Total Plate Count | ≤1000cfu/g | 30cfu/g |
Yeast & Mold | ≤100cfu/g | <10cfu/g |
E.Coli | Negative/g | Negative/g |
Salmonella | Negative/25g | Negative/25g |
Conclusion | Conform with the EP10.0 standard. | |
Storage | Preserve in tight containers, protected from strong light and high heat |