| Customization: | Available |
|---|---|
| CAS No.: | 126-07-8 |
| Formula: | C17h17clo6 |
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| Items | Requirements | Result |
| Appearance | A white or yellowish-white, microfine powder | A white, microfine powder |
| Solubility | Practically insoluble in water, freely soluble in dimethylformamide and in tetrachloroethane, slightly soluble in anhydrous ethanol and in methanol. | Conforms |
| Particle size | The particles of which are generally up to 5um in max. dimension | Conforms |
| Larger particles which may occasionally exceed 30um | Conforms | |
| Melting point | It melts about 220ºC | 221.1ºC |
| Identification | The infrared absorbance spectrum is concordant with the reference spectrum | Conforms |
| Appearance of solution | The solution is clear | Conforms |
| Not more intensely coloured than reference solution Y4. | Conforms | |
| Acidity | Not more than 1.0ml of 0.02M sodium hydroxide is required | 0.45ml |
| Specific optical rotation | +354°to +364° | +359.3° |
| Related substances | Dechologriseofulvin≤3.0% | 0.42% |
| Dehydrogriseofulvin≤ 0.75% | 0.39% | |
| Griseofulvin acid≤2.0% | 0.1% | |
| Other single unknown impurity≤0.15% | Not detected | |
| Total impurity≤5.0% | 0.95% | |
| Loss on drying | ≤1.0% | 0.05% |
| Residue on ignition | ≤0.2% | 0.08% |
| Residual solvents | Ethanol ≤ 0.5% | 0.0020% |
| Acetone ≤ 0.5% | 0.0002% | |
| Dichloromethane ≤ 0.06% | 0.0010% | |
| Assay | 97.0% to 102.0% (dried substance) | 98.3% |
| Conclusion | Tested according to BP2020/EP10, the results meet the standard requirements. | |
Novcare Pharmaceutical is a global trading and Contract manufacturing company specializing in APIs, Pharmaceutical Intermediates, Neutraceuticals, Specialty Chemicals, R&D and Agro Chemicals. we proudly offer a portfolio of internationally recognized products. A combination of Professional leadership, exemplary market knowledge and unrelenting commitment to quality has been instrumental in making Novcare a well-respected name in the business.
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